Purdue-based startup developing technology aimed at helping treat obesity, diabetes

Obesity is also a contributing factor to developing Type 2 diabetes. So, removing excess fat through nanoparticle injections would likely decrease the odds of developing that disease.

WEST LAFAYETTE, Ind. – Imagine being able to turn bad fat into good fat inside your own body without exercising, but rather a simple injection.  

That’s the goal of technology from a Purdue University-based startup, which has received a federal grant for its work to help people struggling with obesity and diabetes.

More than one-third of Americans are obese, and nearly 10 percent have diabetes, according to the Centers for Disease Control and Prevention.

Obesity is also a contributing factor to developing Type 2 diabetes. So, removing excess fat through nanoparticle injections would likely decrease the odds of developing that disease.

Adipo Therapeutics LLC received a Small Business Innovative Research grant of $198,323 from the National Institutes of Health to further develop and optimize its technology platform to help people with obesity and diabetes.

The technology aligns with Purdue's giant leaps celebration, acknowledging the university’s global advancements made in health, space, artificial intelligence and sustainability as part of Purdue’s 150th anniversary. Those are the four themes of the yearlong celebration’s Ideas Festival, designed to showcase Purdue as an intellectual center solving real-world issues.

“Obesity is driven by a systemic energy surplus in bad fat,” said Meng Deng, an assistant professor in Purdue’s Department of Agricultural and Biological Engineering, Weldon School of Biomedical Engineering, and School of Materials Engineering, who founded Adipo. “Built upon our interdisciplinary collaboration with Shihuan Kuang, professor of animal sciences, this funding is very helpful and will allow us to further develop our engineered polymeric nanoparticluate system to safely and effectively convert energy-storing bad fat to energy-burning good fat through regulation of Notch signaling pathway.”

SBIR supports small businesses in the United States by making research and development investments in technologies that have a strong potential for commercialization. A key objective is to translate promising technologies to the private sector and enable life-saving innovations to reach consumer markets.

Photo: Purdue University-based Adipo Therapeutics LLC received a Small Business Innovative Research grant to support technology aimed at converting bad fat to good fat. This image shows bioengineered nanoparticles inducing the conversion of bad fat. (Image provided by Alexander M. Gokan)

Adipo Therapeutics integrates two platform technologies to develop polymer-based nanotherapeutics that act directly on fat tissue and maintain weight loss. 

“Our technology holds great promise to offer unique value with targeted sustainable weight loss, improved glucose control, and minimized off-target side effects,” Deng said. “The support from Purdue Foundry and entrepreneurial ecosystem has been so incredible to help us get this far.”  

Adipo is seeking funding to support further development and clinical translation. The company also seeks partnerships with firms and pharmaceutical companies interested in the technology. Deng can be reached via email at deng65@purdue.edu or by phone at 765-494-1190.

Technology used by Adipo has been licensed through the Purdue Office of Technology Commercialization.

Source: Purdue University

Read more

Comments

No comments to display.

Related posts

Toyota Mobility Foundation announces finalists in $4 million global Mobility Unlimited Challenge

The Challenge invited engineers, innovators, and designers from across the world to submit designs for game-changing technologies, incorporating intelligent systems, to improve the mobility and independence of people with lower-limb paralysis. Central to the Challenge is the importance of collaboration with end-users to develop devices which will integrate seamlessly into users’ lives and environments, while being comfortable and easy to use, enabling greater independence and increased participation in daily life.

PRIMA Call for Proposals: Bridging the gap between potential and actual irrigation performance in the Mediterranean

In the Mediterranean basin, water balances and water used for irrigation including irrigation performance is often lower than potential at the farm and at the water users association level. This gap is evident for average performance, but it is particularly important when the dispersion among farmers and their associations is considered. Attaining Sustainable Mediterranean irrigation requires to assess the real water balances in the area of irrigation, amount of water available for irrigation ensuring that water levels are environmentally safe for ecosystems and other needs. Furthermore, optimising irrigation performance requires to combine technological, managerial and governance innovations taking into account the availability, safety and quality of water resources, existing institutional arrangements, as well as crop agronomy planning.
Application Deadline in a month

PRIMA Call for Proposals: Agro-food Value Chain 2019

Proposals should focus on products with high added value, most exposed to fraud and valorise productions that have been discontinued but hold nutritional value and are important for biodiversity conservation. Proposal should also aim at creating trans-national networks of laboratories, validating and harmonizing protocols, sharing open-data on food products of the Mediterranean tradition, providing a robust support for certification and control bodies, and building capacity in key enabling technologies related to authenticity and traceability.
Application Deadline in a month

African Development Bank Group approves $25 million Equity Investment in Fund for Renewable Energy Projects in Africa

ARPF projects will focus on mature technologies including wind, solar PV, small to medium hydro, geothermal and biomass. These would include grid-connected independent power producers (“IPPs”), and decentralized energy projects (commercial & industrial solar, mini-grids and solar home systems companies). The Fund’s strategy is to prioritize projects with a clear timeline to financial close, with emphasis on de-risking early stage greenfield projects.

European call for proposals: Innovative utilisation of aquatic biomass and Novel aquaculture production systems

The proposals should seek to be complementary with or adding to other projects funded under FP7 and Horizon 2020, ERA-NETs, BBI JU or other funding schemes, both ongoing and recently finished. They should reflect awareness of the objectives of running projects in relevant fields to avoid overlap. Proposed projects must demonstrate industry involvement.
Application Deadline in 2 months

European call for proposals: Sustainable and Resilient agriculture for food and non-food systems

Based on the two previous calls, the FACCE SURPLUS partners decided to further advance their successful funding scheme with a third call of the initiative in order to complete the portfolio of projects and filling remaining research and funding gaps. Having in mind the research already conducted in FACCE SURPLUS projects, this call at the end of the initiative aims at further improving collaboration in the area of food and nonfood biomass production and transformation systems.
Application Deadline in 2 months

A Quick Look At The Latest Happenings In The Cloud Integration Market

As an emerging trend of technology the field of cloud Integration is steadily expanding. The global cloud Integration Market is growing approximately at a CAGR of 8% during 2018-2023 and it is expected to grow at a highest CAGR during the forecast period.

A Close Look At The Latest Research Trends Within The 3D Printing Metals Market

3D printing involves the creation of a 3 dimensional object by adding successive layers of a particular material one on top of each other until the overall object has been formed. Metals constitute one of the main materials used for 3D printing.

Call for Applications: Go Green in the City 2019

The Go Green in the City challenge is now entering its 9th year running and our 2019 edition is going to be even bigger, better and bolder! We are looking for students like you from around the world who are willing to put their skills and ideas to the test.
Application Deadline in 4 months